Drug reference

interferon

Cytokine · Antiviral, Immunomodulator, Antiproliferative

CytokineAntiviral, Immunomodulator, Antiproliferative

CDSCO approved

EXCRETION

—

not curated

INTERACTIONS

—

none in our sources

PREGNANCY

—

not curated

Mechanism

Interferons (IFNs) are potent cytokines that possess antiviral, immunomodulatory, and antiproliferative activities. They have broad-spectrum antiviral activity against respiratory viruses.

Indications

herpesvirus infections (genital HSV, localized herpes zoster in cancer patients or older adults, CMV in renal transplant patients)acyclovir-resistant mucocutaneous HSV infections (topical, in combination with trifluridine)antiretroviral effects in HIV-infected personsHIV-related thrombocytopenia that is resistant to zidovudine therapyrhinovirus colds (prophylactic intranasal IFN-α)refractory condylomata acuminata (genital warts, intralesional injection)verruca vulgaris (intralesional IFN-α)recurrent juvenile laryngeal papillomatosis (systemic)laryngeal disease in older patients (systemic)condyloma acuminatumchronic HCV infectionchronic HBV infectionKaposi sarcoma in HIV-infected patientsother malignanciesmultiple sclerosisidiopathic pulmonary fibrosislaryngeal papillomatosisjuvenile rheumatoid arthritisinfections associated with chronic granulomatous disease