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iron

Antianemic agent

Antianemic agent
CDSCO approved
EXCRETION
not curated
INTERACTIONS
3 major
SEVERE in our sources
PREGNANCY
not curated
Top interactionssee all 12
  • BictegravirSevereDatabaseDDInter
  • DimercaprolSevereDatabaseDDInter
  • DolutegravirSevereDatabaseDDInter

Mechanism

Used as a replacement for natural metabolites in deficiency states (e.g., anaemia).

Drug interactions

Bictegravir
Severe
Database

Clinical effect not specified

Source: DDInter

Dimercaprol
Severe
Database

Clinical effect not specified

Source: DDInter

Dolutegravir
Severe
Database

Clinical effect not specified

Source: DDInter

Alendronate
Moderate
Textbook

Decreased absorption and efficacy of the bisphosphonate.

Oral bisphosphonates should be administered with a full glass of water following an overnight fast and at least 30 min before breakfast to avoid interaction with divalent cations.

Source: G&G 14e · p1060

Antacids
Moderate
Textbook

Reduced absorption of iron.

Separate administration times of antacids and iron supplements to optimize iron absorption.

Source: KDT 7e · p601

Clozapine
Moderate
Textbook

Significant constipation and ileus.

Avoid co-administration.

Source: G&G 14e · p373

Domperidone + Omeprazole
Moderate
Textbook

Decreased iron absorption, potentially leading to iron deficiency.

Source: Harrison 22e · p766

Elvitegravir
Moderate
Textbook

Reduced bioavailability of elvitegravir.

Subject to similar restrictions as raltegravir (take 2h apart, or with food).

Source: G&G 14e · p1245-1266

Pantoprazole + Domperidone
Moderate
Textbook

Decreased iron absorption, potentially leading to iron deficiency.

Source: Harrison 22e · p766

Pariet
Moderate
Textbook

Decreased iron absorption, potentially leading to iron deficiency.

Source: Harrison 22e · p766

Rabeprazole + Domperidone
Moderate
Textbook

Decreased iron absorption, potentially leading to iron deficiency.

Source: Harrison 22e · p766

Tetracyclines
Moderate
Textbook

Poor absorption of tetracycline.

Avoid concurrent ingestion. Dairy products, antacids, aluminum hydroxide gels; calcium, magnesium, iron, or zinc salts; bismuth subsalicylate; and dietary iron and zinc supplements can interfere with absorption of tetracyclines. Omadacycline specifically requires administration on an empty stomach, at least 4 hours after and 2 hours before food consumption. Food, including dairy products, does not interfere with absorption of doxycycline and minocycline but significantly impairs the absorption of omadacycline.

Source: G&G 14e · p1181

Related guidelines

Other Unclassified drugs

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Sources: KD Tripathi 7e·Verified: 2026-05-10 · House clinical team