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lasmiditan

5HT1F Receptor Agonist · Antimigraine

5HT1F Receptor AgonistAntimigraine
CDSCO approved
EXCRETION
not curated
INTERACTIONS
12 major
SEVERE in our sources
PREGNANCY
not curated
Top interactionssee all 12
  • AlfentanilSevereDatabaseDDInter
  • AlmotriptanSevereDatabaseDDInter
  • AmitriptylineSevereDatabaseDDInter
  • AmoxapineSevereDatabaseDDInter

Mechanism

Not yet extracted

Indications

Migraine

Side effects

Serious
  • Fewer adverse cardiovascular events than triptans

Drug interactions

Alfentanil
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Almotriptan
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Amitriptyline
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Amoxapine
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Berotralstat
Severe
Database

Drug interaction classified as: absorption

Source: DDInter

Buspirone
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Citalopram
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Clomipramine
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Colchicine
Severe
Database

Drug interaction classified as: excretion

Source: DDInter

Cyclobenzaprine
Severe
Database

Clinical effect not specified

Source: DDInter

Desipramine
Severe
Database

Clinical effect not specified

Source: DDInter

Desvenlafaxine
Severe
Database

Clinical effect not specified

Source: DDInter

Related guidelines

Ask House about lasmiditan

Continue into a citation-backed clinical answer with the drug context already attached.

Sources: Goodman & Gilman 14e·Verified: 2026-05-10 · House clinical team