Bupropion
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Drug reference
Lindane
Antiparasitic · Ectoparasiticide
Also known as gamma-hexachlorocyclo-hexane
AntiparasiticEctoparasiticide
CDSCO approvedSchedule H
EXCRETION
—
not curated
INTERACTIONS
4 major
SEVERE in our sources
PREGNANCY
—
not curated
Top interactions
- BupropionSevereDatabaseDDInter
- IohexolSevereDatabaseDDInter
- IopamidolSevereDatabaseDDInter
- TramadolSevereDatabaseDDInter
Mechanism
Lindane is an organochloride compound that induces neuronal hyperstimulation and eventual paralysis of parasites.
Indications
PediculosisScabiesheadlice
Dosing
- Adult
- The usual dosages of antimalarials are 200 mg twice a day. (maximum of 6.5 mg/kg/day) of hydroxychloroquine, 250-500. mg/day (maximum of 3 mg/kg/day) of chloroquine, and 100-200. antimalarials (100 mg of hydroxychloroquine or 125 mg of chloroquine two to three times weekly) to avoid severe hepatotoxicity.. mg/wk (maximum of 15 mg/wk). This dosage may be increased
Pharmacokinetics
Half-life
~24 hr
Metabolism
induces CYP isoenzymes in liver
Contraindications
- Children and adults weighing <110 pounds
- Patients with underlying skin disorders such as atopic dermatitis
- infants
- young children
- pregnancy
Side effects
Serious
- Neurotoxicity
- CNS stimulation
- vertigo
- convulsions (especially in children)
- cardiac arrhythmias
Drug interactions
Iohexol
Severe
Database
Clinical effect not specified
Source: DDInter
Iopamidol
Severe
Database
Clinical effect not specified
Source: DDInter
Tramadol
Severe
Database
Clinical effect not specified
Source: DDInter
8 additional low-confidence interactions hidden — those rows lack a documented mechanism or management plan in our sources.
Other Antiparasitic drugs
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Sources: KD Tripathi 7e·Verified: 2026-05-10 · House clinical team