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Drug reference

Permethrin

Antiparasitic · Antiparasitic, Scabicide

AntiparasiticAntiparasitic, Scabicide
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
—
none in our sources
PREGNANCY
—
not curated

Mechanism

Permethrin acts as a pyrethroid insecticide and acaricide. For scabies, it penetrates the skin crusts to kill mites.

Indications

Treatment of scabies (Sarcoptes scabiei)scabieslice

Dosing

Adult
For scabies, apply 30-60g topically to the whole body, including the scalp, neck, face, ears, webs of fingers and toes, and under nails. Apply twice, one week apart. Reapply to hands if they are washed. For hyperkeratotic scabies, 2 or 3 applications on consecutive days may be required.

Side effects

Common
mild and transient burningitchingtinglingerythemarash

Drug interactions

3 additional unreviewed or low-confidence interactions hidden because their provenance or source detail is insufficient.

Other Antiparasitic drugs

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Textbook-sourced·Sources: KD Tripathi 7e, Katzung, BNF, Nelson·Updated: 2026-05-10