Drug reference
meclozine
H1 antihistaminic (moderately sedative) · Antihistaminic, Antiemetic
H1 antihistaminic (moderately sedative)Antihistaminic, Antiemetic
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
—
none in our sources
PREGNANCY
—
not curated
Mechanism
H1 antagonism. Also has anticholinergic action.
Indications
motion sickness (prophylactic, milder types)sea sickness
Dosing
- Adult
- 25–50 mg oral
Pharmacokinetics
Duration
12–24 hours or more
Side effects
Common
sedationdiminished alertnesslight headednessmotor incoordinationfatiguetendency to fall asleepdry mouthalteration of bowel movementurinary hesitancyblurring of vision
Related guidelines
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Sources: KD Tripathi 7e·Verified: 2026-05-10 · House clinical team