Alfentanil
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Drug reference
metaxalone
Muscle relaxant (sedative properties) · Muscle relaxant
Muscle relaxant (sedative properties)Muscle relaxant
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
12 major
SEVERE in our sources
PREGNANCY
—
not curated
Top interactionssee all 12 →
- AlfentanilSevereDatabaseDDInter
- BenzhydrocodoneSevereDatabaseDDInter
- BuprenorphineSevereDatabaseDDInter
- ButorphanolSevereDatabaseDDInter
Mechanism
Relies on sedative properties and blockade of nociceptive pathways.
Indications
Muscle relaxation
Drug interactions
Benzhydrocodone
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Buprenorphine
Severe
Database
Drug interaction classified as: synergy.
Source: DDInter
Butorphanol
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Codeine
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Dextropropoxyphene
Severe
Database
Clinical effect not specified
Source: DDInter
Dezocine
Severe
Database
Clinical effect not specified
Source: DDInter
Dihydrocodeine
Severe
Database
Clinical effect not specified
Source: DDInter
Fentanyl
Severe
Database
Drug interaction classified as: synergy.
Source: DDInter
Hydrocodone
Severe
Database
.
Source: DDInter
Hydromorphone
Severe
Database
.
Source: DDInter
Leflunomide
Severe
Database
Clinical effect not specified
Source: DDInter
Other Muscle relaxant (sedative properties) drugs
Ask House about metaxalone
Continue into a citation-backed clinical answer with the drug context already attached.
Sources: Goodman & Gilman 14e·Verified: 2026-05-10 · House clinical team