Alfentanil
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Drug reference
orphenadrine
Muscle relaxant (sedative properties) · Muscle relaxant
Muscle relaxant (sedative properties)Muscle relaxant
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
12 major
SEVERE in our sources
PREGNANCY
—
not curated
Top interactionssee all 12 →
- AlfentanilSevereDatabaseDDInter
- BenzhydrocodoneSevereDatabaseDDInter
- BuprenorphineSevereDatabaseDDInter
- ButorphanolSevereDatabaseDDInter
Mechanism
Relies on sedative properties and blockade of nociceptive pathways.
Indications
Muscle relaxationParkinson's disease (mild cases, or combined with levodopa to lower its dose)Drug-induced parkinsonism
Dosing
- Adult
- 100–300 mg/day.
Side effects
Common
sedationmild euphoriant action
Drug interactions
Benzhydrocodone
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Buprenorphine
Severe
Database
Drug interaction classified as: synergy.
Source: DDInter
Butorphanol
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Codeine
Severe
Database
Drug interaction classified as: synergy.
Source: DDInter
Dextropropoxyphene
Severe
Database
Clinical effect not specified
Source: DDInter
Dezocine
Severe
Database
Clinical effect not specified
Source: DDInter
Dihydrocodeine
Severe
Database
Clinical effect not specified
Source: DDInter
Fentanyl
Severe
Database
Drug interaction classified as: synergy.
Source: DDInter
Hydrocodone
Severe
Database
.
Source: DDInter
Hydromorphone
Severe
Database
.
Source: DDInter
Levacetylmethadol
Severe
Database
Clinical effect not specified
Source: DDInter
Related guidelines
Other Muscle relaxant (sedative properties) drugs
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Textbook-sourced·Sources: KD Tripathi 7e, Goodman & Gilman 14e·Updated: 2026-05-10