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Drug reference

monobenzone

Potent demelanizing agent · Demelanizing agent

Potent demelanizing agentDemelanizing agent
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
—
none in our sources
PREGNANCY
—
not curated

Mechanism

Destroys melanocytes, causing permanent depigmentation.

Indications

Widespread vitiligo (to reduce color contrast)Post-inflammatory melasma

Dosing

Adult
5% lotion or 20% ointment, applied 2–3 times daily

Side effects

Common
Irregular bleaching resulting in depigmented patchesErythemaEczema

Related guidelines

Inflammatory bowel disease
OTHER · Gastroenterology · 2015
Preventive care in inflammatory bowel disease
ACG · Gastroenterology · 2025
Atrial fibrillation
ESC · Cardiology · 2020
Coronary angiography with renal dysfunction
CSI · Cardiology · 2020
Chronic heart failure in adults
NICE · Cardiology · 2018

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Textbook-sourced·Sources: KD Tripathi 7e·Updated: 2026-05-10