Drug reference

oxantel pamoate

Tetrahydropyrimidine analogue · Anthelmintic

Tetrahydropyrimidine analogueAnthelmintic

CDSCO approved

EXCRETION

—

not curated

INTERACTIONS

—

none in our sources

PREGNANCY

—

not curated

Mechanism

Oxantel pamoate is a depolarizing neuromuscular blocking agent that opens nonselective cation channels and induces persistent activation of nicotinic acetylcholine receptors, specifically the N subtype, leading to spastic paralysis of the worm.

Indications

mixed infections with Trichuris trichiuraascariasistrichuriasishookworm infections

Pharmacokinetics

Metabolism

Poorly absorbed from the GI tract.

Excretion

Major proportion of administered dose recovered in feces.

Side effects

Common

transient GI symptomsheadachedizzinessrashfever

Related guidelines

Skin and soft tissue infections

IDSA · Infectious Diseases · 2010

Urinary tract infection

EAU · Urology · 2024

Other Tetrahydropyrimidine analogue drugs

pyrantel pamoate

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Sources: Goodman & Gilman 14e·Verified: 2026-05-10 · House clinical team