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Drug reference

oxytetracycline

Tetracycline · Antibacterial

TetracyclineAntibacterialATC null
CDSCO approved
EXCRETION
not curated
INTERACTIONS
7 major
SEVERE in our sources
PREGNANCY
X
FDA category + note
Top interactionssee all 7
  • AcitretinSevereDatabaseDDInter
  • IsotretinoinSevereDatabaseDDInter
  • LomitapideSevereDatabaseDDInter
  • MipomersenSevereDatabaseDDInter

Mechanism

Inhibits protein synthesis.

Contraindications

  • Below 6 years (deposits in developing teeth and bone, discolors and weakens them)
  • Pregnancy (acute yellow atrophy of liver, pancreatitis and kidney damage in mother; teeth and bone deformities in offspring)

Side effects

Common
Local irritancySuperinfection risk (especially diarrhoea)Pseudomembranous enterocolitis
Serious
  • Liver and kidney damage
  • Antianabolic effect

Pregnancy & lactation

Pregnancy

X

Drug interactions

Acitretin
Severe
Database

Clinical effect not specified

Source: DDInter

Isotretinoin
Severe
Database

Clinical effect not specified

Source: DDInter

Lomitapide
Severe
Database

Clinical effect not specified

Source: DDInter

Mipomersen
Severe
Database

Clinical effect not specified

Source: DDInter

Pexidartinib
Severe
Database

Clinical effect not specified

Source: DDInter

Tretinoin
Severe
Database

Clinical effect not specified

Source: DDInter

Vitamin A
Severe
Database

Clinical effect not specified

Source: DDInter

5 additional low-confidence interactions hidden — those rows lack a documented mechanism or management plan in our sources.

Other Tetracycline drugs

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Sources: KD Tripathi 7e·Verified: 2026-05-10 · House clinical team