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Paricalcitol

Vitamin · Management of secondary hyperparathyroidism

VitaminManagement of secondary hyperparathyroidism
CDSCO approved
EXCRETION
not curated
INTERACTIONS
10 major
SEVERE in our sources
PREGNANCY
not curated
Top interactionssee all 10
  • Aluminum HydroxideSevereDatabaseDDInter
  • BurosumabSevereDatabaseDDInter
  • CalcifediolSevereDatabaseDDInter
  • CalcitriolSevereDatabaseDDInter

Mechanism

Paricalcitol is a synthetic vitamin D analogue. It is used for the prevention and treatment of secondary hyperparathyroidism associated with chronic kidney disease.

Indications

Prevention and treatment of secondary hyperparathyroidism associated with chronic kidney diseasePrevention and treatment of secondary hyperparathyroidism associated with chronic renal failure in patients on haemodialysissecondary hyperparathyroidism in patients with chronic kidney disease (CKD)

Dosing

Adult
Oral: Consult product literature. Parenteral (via haemodialysis access): Consult product literature.

Side effects

Common
Electrolyte imbalanceHypoparathyroidismTaste altered
Serious
  • Angioedema
  • Laryngeal oedema
  • Cardiac arrest
  • Cerebrovascular insufficiency
  • Coma
  • Pneumonia
  • Arrhythmias
  • Asthma
  • Breast cancer

Drug interactions

Aluminum Hydroxide
Severe
Database

Drug interaction classified as: absorption

Source: DDInter

Burosumab
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Calcifediol
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Calcitriol
Severe
Database

Drug interaction classified as: synergy.

Source: DDInter

Cholecalciferol
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Dihydrotachysterol
Severe
Database

Clinical effect not specified

Source: DDInter

Doxercalciferol
Severe
Database

Clinical effect not specified

Source: DDInter

Erdafitinib
Severe
Database

Drug interaction classified as: others

Source: DDInter

Ergocalciferol
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Sucralfate
Severe
Database

Clinical effect not specified

Source: DDInter

2 additional low-confidence interactions hidden — those rows lack a documented mechanism or management plan in our sources.

Related guidelines

Other Vitamin drugs

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Sources: Goodman & Gilman 14e, Katzung, BNF·Verified: 2026-05-10 · House clinical team