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penicillin g, aqueous crystalline

Antibiotic, Penicillin

Antibiotic, Penicillin
CDSCO approved
EXCRETION
not curated
INTERACTIONS
none in our sources
PREGNANCY
B
FDA category + note

Mechanism

Penicillin G is an antibiotic that kills Treponema pallidum by interfering with bacterial cell wall synthesis. T. pallidum is susceptible to very low concentrations of penicillin G, and this aqueous formulation produces treponemicidal concentrations in cerebrospinal fluid (CSF) for effective treatment of neurosyphilis.

Indications

NeurosyphilisOcular syphilisOtic syphilis

Pregnancy & lactation

Pregnancy

B

Related guidelines

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Sources: Harrison 22e·Verified: 2026-05-10 · House clinical team