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penicillin g benzathine

Antibiotic, Penicillin

Antibiotic, Penicillin
CDSCO approved
EXCRETION
not curated
INTERACTIONS
none in our sources
PREGNANCY
B
FDA category + note

Mechanism

Penicillin G is an antibiotic that kills Treponema pallidum by interfering with bacterial cell wall synthesis. T. pallidum is susceptible to very low concentrations of penicillin G, but a long period of exposure is required due to the organism's unusually slow rate of multiplication.

Indications

Primary syphilis (CSF normal or not examined)Secondary syphilis (CSF normal or not examined)Early latent syphilis (CSF normal or not examined)Late latent syphilis (CSF normal or not examined)Latent syphilis of unknown duration (CSF normal or not examined)Cardiovascular syphilis (CSF normal or not examined)Late benign syphilis (Gumma) (CSF normal or not examined)Preventive treatment of individuals exposed to infectious syphilis within the previous 3 monthsSyphilis in pregnancy (according to stage)

Pregnancy & lactation

Pregnancy

B

Related guidelines

Other Unclassified drugs

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Sources: Harrison 22e·Verified: 2026-05-10 · House clinical team