Drug reference

quinacrine

Antiprotozoal agent

CDSCO approved

EXCRETION

—

not curated

INTERACTIONS

1 major

SEVERE in our sources

PREGNANCY

FDA category + note

Top interactions

PrimaquineSevereTextbookHarrison 22e · p1741

Mechanism

Not yet extracted

Pharmacokinetics

Bioavailability

rapidly absorbed from the intestinal tract

Metabolism

widely distributed in body tissues

Side effects

Common

headachenauseavomitingbitter tasteyellow-orange discoloration of skin, sclerae, urine

Serious

psychosis
exfoliative dermatitis
retinopathy
g6pd-induced hemolysis
exacerbation of psoriasis
disulfiram-like effects

Pregnancy & lactation

Pregnancy

Drug interactions

Primaquine

Severe

Textbook

Increased toxicity of primaquine, potentially leading to severe adverse effects.

Not specified in the text, but likely contraindication or very cautious use with close monitoring.

Source: Harrison 22e · p1741

Other Unclassified drugs

5-9-tetrahydrocannabinol

adrenochrome monosemicarbazone

0 brands

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Sources: Harrison 22e·Verified: 2026-05-10 · House clinical team