Cidofovir
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Drug reference
rofecoxib
COX-2 inhibitor (coxib) · Anti-inflammatory, Analgesic
COX-2 inhibitor (coxib)Anti-inflammatory, Analgesic
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
11 major
incl. contraindicated
PREGNANCY
—
not curated
Top interactionssee all 11 →
- CidofovirSevereDatabaseDDInter
- DeferasiroxSevereDatabaseDDInter
- DiatrizoateSevereDatabaseDDInter
- EverolimusSevereDatabaseDDInter
Mechanism
Selectively inhibits cyclooxygenase-2 (COX-2).
Contraindications
- Withdrawn from market due to cardiovascular risk profile
Side effects
Serious
- Increased incidence of myocardial infarction
- Increased incidence of stroke
- Increased incidence of vascular death
- Cardiovascular risk
Drug interactions
Deferasirox
Severe
Database
Clinical effect not specified
Source: DDInter
Diatrizoate
Severe
Database
Clinical effect not specified
Source: DDInter
Everolimus
Severe
Database
Clinical effect not specified
Source: DDInter
Human Cytomegalovirus Immune Globulin
Severe
Database
Clinical effect not specified
Source: DDInter
Inotersen
Severe
Database
Clinical effect not specified
Source: DDInter
Iohexol
Severe
Database
Clinical effect not specified
Source: DDInter
Iopamidol
Severe
Database
Clinical effect not specified
Source: DDInter
Iopromide
Severe
Database
Clinical effect not specified
Source: DDInter
Iothalamic Acid
Severe
Database
Clinical effect not specified
Source: DDInter
Ioversol
Severe
Database
Clinical effect not specified
Source: DDInter
1 additional unreviewed or low-confidence interaction hidden because their provenance or source detail is insufficient.
Related guidelines
Other COX-2 inhibitor (coxib) drugs
Ask House about rofecoxib
Continue into a citation-backed clinical answer with the drug context already attached.
Textbook-sourced·Sources: Goodman & Gilman 14e·Updated: 2026-05-10