House
Sign inCreate account
Drug lookup
Drug reference

sertindole

second-generation antipsychotic · Antipsychotic

second-generation antipsychoticAntipsychotic
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
—
none in our sources
PREGNANCY
C
FDA category + note

Mechanism

Sertindole is a 5HT2a and D2 antagonist.

Indications

Schizophrenia

Dosing

Adult
4–16 mg/day (oral)

Side effects

Common
Low risk of metabolic adverse effects
Serious
  • QTc prolongation
  • torsades de pointes (historical reports, reintroduction with extensive monitoring)

Pregnancy & lactation

Pregnancy

C

Lactation

Not specified

Related guidelines

Schizophrenia
APA · Psychiatry · 2020
Stroke and TIA — secondary prevention
AHA · Neurology · 2021
Schizophrenia
IPS · Psychiatry · 2017
Dyslipidaemia management
ICMR · Cardiology · 2023
Glomerular diseases
KDIGO · Nephrology · 2021

Other second-generation antipsychotic drugs

lumateperone
0 brands

Ask House about sertindole

Continue into a citation-backed clinical answer with the drug context already attached.

Open in workspaceAsk House about this drug

Sources: Goodman & Gilman 14e·Verified: 2026-05-10 · House clinical team