Alfentanil
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Drug reference
tasimelteon
Melatonin Congener · Hypnotic
Melatonin CongenerHypnotic
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
12 major
SEVERE in our sources
PREGNANCY
—
not curated
Top interactionssee all 12 →
- AlfentanilSevereDatabaseDDInter
- ApalutamideSevereDatabaseDDInter
- BenzhydrocodoneSevereDatabaseDDInter
- BuprenorphineSevereDatabaseDDInter
Mechanism
Tasimelteon is a selective agonist for MT1 and MT2 receptors.
Indications
Non–24-h sleep-wake syndrome in totally blind patientsNighttime sleep disturbances in adults and children with Smith-Magenis syndrome
Drug interactions
Apalutamide
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Benzhydrocodone
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Buprenorphine
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Butorphanol
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Carbamazepine
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Ciprofloxacin
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Codeine
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Dextropropoxyphene
Severe
Database
Clinical effect not specified
Source: DDInter
Dezocine
Severe
Database
Clinical effect not specified
Source: DDInter
Dihydrocodeine
Severe
Database
Clinical effect not specified
Source: DDInter
Enoxacin
Severe
Database
Clinical effect not specified
Source: DDInter
Related guidelines
Empirical antimicrobial use in common syndromes
ICMR · Infectious Diseases · 2019
Acute coronary syndrome in chronic kidney disease
CSI · Cardiology · 2020
Sjögren's syndrome
EULAR · Rheumatology · 2025
Acute diarrhoea in children
IAP · Pediatrics · 2022
Primary PCI for acute coronary syndrome
ESC · Cardiology · 2026
Other Melatonin Congener drugs
Ask House about tasimelteon
Continue into a citation-backed clinical answer with the drug context already attached.
Sources: Goodman & Gilman 14e·Verified: 2026-05-10 · House clinical team