taxanes

Significantly alters drug clearance and toxicity of taxanes (paclitaxel, docetaxel, cabazitaxel).

Monitor taxane levels or clinical effects, and adjust taxane dosage as needed when co-administered with antifungal imidazoles.

Source: G&G 14e

Potential for increased taxane levels and toxicity.

Monitor taxane levels or clinical effects, and adjust taxane dosage as needed when co-administered with estramustine.

Source: G&G 14e

Significantly alters drug clearance and toxicity of taxanes (paclitaxel, docetaxel, cabazitaxel).

Monitor taxane levels or clinical effects, and adjust taxane dosage as needed when co-administered with phenobarbital.

Source: G&G 14e

Significantly alters drug clearance and toxicity of taxanes (paclitaxel, docetaxel, cabazitaxel).

Monitor taxane levels or clinical effects, and adjust taxane dosage as needed when co-administered with phenytoin.

Source: G&G 14e

Increased trastuzumab exposure / additive toxicity (regimen)

Standard regimen monitoring

Source: Kimi deep-research + Cla