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Drug reference

trastuzumab emtansine

Drug monograph

CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
12 major
SEVERE in our sources
PREGNANCY
—
not curated
Top interactionssee all 12 →
  • AbciximabSevereDatabaseDDInter
  • AcalabrutinibSevereDatabaseDDInter
  • AnisindioneSevereDatabaseDDInter
  • ApixabanSevereDatabaseDDInter

Mechanism

An antibody-drug conjugate (ADC) that combines trastuzumab with a cytotoxic agent, delivering chemotherapy directly to HER2-expressing cells.

Indications

For HER2-positive patients with residual invasive disease at surgery after neoadjuvant therapy, to complete a year of therapy

Drug interactions

Abciximab
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Acalabrutinib
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Anisindione
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Apixaban
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Ardeparin
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Argatroban
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Aspirin
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Avapritinib
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Betrixaban
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Bivalirudin
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Cabozantinib
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Cangrelor
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Related guidelines

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OTHER · Gastroenterology · 2016
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OTHER · Gastroenterology · 2015
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KDIGO · Nephrology · 2024
Invasive candidiasis
IDSA · Infectious Diseases · 2016
Preoperative cardiac evaluation for non-cardiac surgery
AHA · Cardiology · 2025

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Textbook-sourced·Sources: Harrison 22e·Updated: 2026-05-10