Drug reference

Travoprost

Vasodilator · Glaucoma and ocular hypertension

VasodilatorGlaucoma and ocular hypertensionATC S01EE04

CDSCO approvedSchedule HATC S01EE04

EXCRETION

—

not curated

INTERACTIONS

—

none in our sources

PREGNANCY

—

not curated

Mechanism

Travoprost is a selective FP-prostanoid receptor agonist that primarily lowers intraocular pressure (IOP) by increasing the uveoscleral outflow of aqueous humor. It also has a minor effect on enhancing trabecular outflow. This combined action effectively reduces IOP, preventing the progression of glaucoma and preserving visual function.

Indications

Ocular hypertension (intra-ocular pressure 24 mmHg or greater and at risk of visual impairment)Suspected chronic open-angle glaucoma (intra-ocular pressure 24 mmHg or greater)Chronic open-angle glaucomaAdvanced chronic open-angle glaucoma (initiated and continued until surgery takes place)glaucomaocular hypertensionOpen angle glaucomaWide angle glaucoma

Dosing

Adult: l INDICATIONS AND DOSE Chronic open-angle glaucoma | Ocular hypertension ▶ TO THE EYE ▶ Adult: Apply twice daily Also consider contra-indications listed for systemically administered beta blockers . bradycardia .…

Pharmacokinetics

Duration

24 hours or more

Side effects

Common

lash growthallergic conjunctival hyperemiapermanent increase in iris pigmentationorbital fat atrophySimilar to latanoprost (ocular irritation, pain, blurring, iris pigmentation, eyelash changes)

Serious