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Drug reference

valnoctamide

Tranquilizer

Tranquilizer
CDSCO approved
EXCRETION
not curated
INTERACTIONS
none in our sources
PREGNANCY
not curated

Mechanism

Valnoctamide inhibits microsomal epoxide hydrolase (mEH).

Drug interactions

Carbamazepine
Moderate
Textbook

Elevation in plasma concentrations of the active carbamazepine-10,11-epoxide metabolite and consequent side effects.

This interaction has led to efforts to develop new antiepileptic drugs (e.g., gabapentin, levetiracetam) that are metabolized by CYPs and not by EHs.

Source: G&G 14e · p107

Other Unclassified drugs

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Sources: Goodman & Gilman 14e·Verified: 2026-05-10 · House clinical team