Drug reference

beclomethasone dipropionate

Inhaled corticosteroid · Anti-asthmatic, Anti-inflammatory (pulmonary), Corticosteroid (inhaled), Anti-allergic rhinitis (nasal spray for ciclesonide prodrug usage noted, applicable here too for general ICS class info about nasal sprays later in the book likely not this chapter, but contextually for BDP, it's focused on pulmonary). I will stick to pulmonary categories directly supported by the text for BDP. The text explicitly mentions ciclesonide nasal spray. For BDP, it's

Inhaled corticosteroidAnti-asthmatic, Anti-inflammatory (pulmonary), Corticosteroid (inhaled), Anti-allergic rhinitis (nasal spray for ciclesonide prodrug usage noted, applicable here too for general ICS class info about nasal sprays later in the book likely not this chapter, but contextually for BDP, it's focused on pulmonary). I will stick to pulmonary categories directly supported by the text for BDP. The text explicitly mentions ciclesonide nasal spray. For BDP, it's

CDSCO approved

EXCRETION

—

not curated

INTERACTIONS

—

none in our sources

PREGNANCY

FDA category + note

Mechanism

Not yet extracted

Indications

Persistent asthma (when inhaled β2 agonists are required almost daily or the disease is not only episodic)Prophylaxis of asthmaPerennial rhinitis (intranasal spray)Variety of dermatological conditionsSevere inflammatory conditionsUnresponsive eczemaPsoriasis

Dosing

Adult: 100–200 µg BD, titrate dose upward every 3–5 days; max 400 µg QID by inhalation (for asthma). 50 µg in each nostril BD–TDS (intranasal spray for perennial rhinitis).

Pharmacokinetics

Bioavailability

Low systemic activity due to poor absorption and/or marked first-pass metabolism

Contraindications

No role during an acute attack or in status asthmaticus

Side effects

Common

Hoarseness of voiceDysphoniaSore throatAsymptomatic or symptomatic oropharyngeal candidiasisThinning of epidermisDermal atrophyTelangiectasiaStriaeEasy bruisingHypopigmentationDelayed wound healingFungal and bacterial infections

Serious