Drug reference
bezlotoxumab
Monoclonal antibody · Anti-infective (monoclonal antibody)
Monoclonal antibodyAnti-infective (monoclonal antibody)
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
—
none in our sources
PREGNANCY
—
not curated
Mechanism
Bezlotoxumab is a monoclonal antibody directed against Clostridioides difficile toxin B. It works by neutralizing the toxin, thereby reducing the risk of rCDI.
Indications
Adjuvant therapy for patients at high risk for recurrent Clostridioides difficile infection (rCDI) who are receiving vancomycin, fidaxomicin, or metronidazole.
Dosing
- Adult
- 10 mg/kg given IV
Related guidelines
Other Monoclonal antibody drugs
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Textbook-sourced·Sources: Harrison 22e·Updated: 2026-05-10