Drug reference

calcium gluconate

Calcium Supplement · Electrolyte Supplement

Calcium SupplementElectrolyte Supplement

CDSCO approved

EXCRETION

—

not curated

INTERACTIONS

5 major

SEVERE in our sources

PREGNANCY

—

not curated

Top interactionssee all 5 →

BictegravirSevereDatabaseDDInter
CeftriaxoneSevereDatabaseDDInter
DigitoxinSevereDatabaseDDInter
DigoxinSevereDatabaseDDInter

Mechanism

Calcium gluconate provides calcium ions to the body. In hyperkalaemia, it temporarily protects against myocardial excitability and reduces the toxic effects of hyperkalaemia. In hypocalcaemia, it replenishes deficient calcium levels to correct the imbalance.

Indications

Acute severe hyperkalaemia (plasma-potassium concentration above 6.5 mmol/litre or in the presence of ECG changes)Severe acute hypocalcaemiaHypocalcaemic tetanysevere hypocalcemic tetanymoderate-to-severe hypocalcemiaextreme hyperkalemia (serum K+ >7 mEq/L)Tetany (immediate treatment of severe cases)Dietary supplement (growing children, pregnant, lactating and menopausal women)Osteoporosis (adjuvant role to alendronate/HRT/raloxifene)Empirically used in dermatoses, paresthesias, weakness

Dosing

Adult: For acute severe hyperkalaemia: 10% solution by slow intravenous injection, titrated and adjusted to ECG improvement. For severe acute hypocalcaemia or hypocalcaemic tetany: initial slow intravenous injection of 10% solution, with plasma-calcium and ECG monitoring; may be repeated as required or followed by continuous intravenous infusion to prevent recurrence.
Pediatric: Children 1–10 yr: 0.8–1.2 g; Young adult 11–24 yr: 1.2–1.5 g