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Imiquimod

Immunosuppressant · Antiviral (Topical), Antineoplastic (Topical), Immunomodulator

Also known as ALDARA

ImmunosuppressantAntiviral (Topical), Antineoplastic (Topical), Immunomodulator
CDSCO approvedSchedule H
EXCRETION
not curated
INTERACTIONS
1 major
SEVERE in our sources
PREGNANCY
Patient packs for topical preparations carry a
FDA category + note
Top interactions
  • Aminolevulinic AcidSevereDatabaseDDInter

Mechanism

Imiquimod produces a more marked inflammatory reaction than diclofenac sodium. It is used in immunotherapy, suggesting it modifies the immune response.

Indications

Actinic keratosisSuperficial basal cell carcinomasAcyclovir-resistant cutaneous herpesAnogenital warts (condylomata acuminata)superficial basal cell carcinomagenital and anal wartslentigo maligna in cosmetically sensitive locations with narrow resection marginslow-volume dermal lesions of melanomasuperficial and smaller nodular BCCs (not FDA approved for nodular BCC)Extramammary Paget’s disease (for more extensive disease)field therapy for actinic keratosesgenital warts

Dosing

Adult
l INDICATIONS AND DOSE enzacamene 4-methylbenzylidene camphor SOLARAZE ® Actinic keratosis octinoxate octyl (or ethylhexyl) methoxycinnamate ▶ TO THE SKIN octocrilene octocrylene oxybenzone benzophenone-3 The European Commission Cosmetic Products Regulation (EC) 1223/2009 requires the use of INCI (International Nomenclature of Cosmetic Ingredients) for cosmetics and sunscreens.…

Side effects

Common
Inflammatory reactionLocal inflammatory side effects

Pregnancy & lactation

Pregnancy

Patient packs for topical preparations carry a

Drug interactions

Aminolevulinic Acid
Severe
Database

Clinical effect not specified

Source: DDInter

3 additional low-confidence interactions hidden — those rows lack a documented mechanism or management plan in our sources.

Related guidelines

Other Immunosuppressant drugs

Ask House about Imiquimod

Continue into a citation-backed clinical answer with the drug context already attached.

Sources: Goodman & Gilman 14e, Harrison 22e, BNF·Verified: 2026-05-13 · House clinical team