Metaraminol

Metaraminol is a direct-acting sympathomimetic amine. It primarily exerts its effects by activating alpha-adrenergic receptors, leading to widespread vasoconstriction. This action results in an increase in systemic vascular resistance and subsequently, blood pressure, making it useful as a pressor agent.

Adult

Emergency treatment of acute hypotension: Initially 0.5–5 mg by intravenous injection, then 15–100 mg by intravenous infusion, adjusted according to response. Acute hypotension: 15–100 mg by intravenous infusion, adjusted according to response.

• Cirrhosis
• Coronary vascular thrombosis
• Diabetes mellitus
• Extravasation at injection site may cause necrosis
• Following myocardial infarction
• Hypercapnia
• Hypertension
• Hyperthyroidism
• Hypoxia
• Mesenteric vascular thrombosis
• Peripheral vascular thrombosis
• Prinzmetal’s variant angina
• Uncorrected hypovolaemia