pertussis vaccine

It is a suspension of killed B. pertussis organisms. It induces specific antibodies and also a state of diminished β adrenergic reactivity, aiding sensitization to other antigens.

Pediatric

0.25–0.5 ml s.c. or i.m. thrice at 4 week intervals in infants and children below 5 years.

• History of severe systemic reaction to previous dose (high fever with hypotonic hyporesponsive child, convulsions, alterations of consciousness, focal neurological signs)
• Children with history of convulsions
• Children with other neurological disease