Drug reference
vi typhoid polysaccharide vaccine
Killed (Inactivated) bacterial vaccine · Vaccine for typhoid
Killed (Inactivated) bacterial vaccineVaccine for typhoid
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
—
none in our sources
PREGNANCY
—
not curated
Mechanism
The vaccine contains purified Vi capsular antigen of S. typhi. It induces an immune response against S. typhi.
Indications
Protection against S. typhi
Dosing
- Adult
- Single 0.5 ml s.c./i.m. dose; repeat after 3 years.
- Pediatric
- Single 0.5 ml s.c./i.m. dose; repeat after 3 years. Not approved for children below 2 years.
Pharmacokinetics
Duration
Protection at 18 months: 72%, Protection at 3 years: 60%
Contraindications
- Children below 2 years
- Pregnant women
Side effects
Common
Much less local and systemic side effects compared to TAB
Related guidelines
Other Killed (Inactivated) bacterial vaccine drugs
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Textbook-sourced·Sources: KD Tripathi 7e·Updated: 2026-05-10