Drug reference

polygeline

Plasma expander, Degraded gelatin polymer · Plasma expander

Plasma expander, Degraded gelatin polymerPlasma expander

CDSCO approved

EXCRETION

—

not curated

INTERACTIONS

—

none in our sources

PREGNANCY

—

not curated

Mechanism

Polygeline is a polypeptide with an average molecular weight of 30,000, which exerts oncotic pressure similar to human albumin. When infused intravenously, it retains fluid within the vascular compartment.

Indications

Hypovolemia due to loss of plasma/blood (as substitute for plasma)Burns (acute phase only)Hypovolemic and endotoxin shockSevere trauma and extensive tissue damageTemporary measure in cases of whole blood lossPriming of heart-lung and dialysis machines