Drug reference

Romosozumab

Monoclonal Antibody · Osteoporosis treatment

Also known as Evenity

Monoclonal AntibodyOsteoporosis treatment

CDSCO approvedSchedule H

EXCRETION

—

not curated

INTERACTIONS

1 major

SEVERE in our sources

PREGNANCY

—

not curated

Top interactions

EtelcalcetideSevereDatabaseDDInter

Mechanism

Romosozumab is an antibody that inhibits sclerostin. Sclerostin is a protein that blocks osteoblast proliferation by inhibiting the Wnt pathway. By inhibiting sclerostin, romosozumab promotes osteoblast proliferation and bone formation. It also initially suppresses osteoclast activity.

Indications

Treatment of osteoporosispostmenopausal women with osteoporosis

Dosing

Adult: range of doses that are generally regarded as being suitable for adults. Complementary and alternative medicine Prescribing unlicensed medicines An increasing amount of information on complementary and alternative medicine is becoming available.…