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sulbactam

β-Lactamase Inhibitor · β-Lactamase Inhibitor (Co-formulated with β-lactam antibiotics)

β-Lactamase Inhibitorβ-Lactamase Inhibitor (Co-formulated with β-lactam antibiotics)
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
—
none in our sources
PREGNANCY
—
not curated

Mechanism

Sulbactam is a β-lactamase inhibitor similar in structure to clavulanic acid. It also possesses intrinsic activity against Acinetobacter spp.

Pharmacokinetics

Bioavailability
oral absorption is inconsistent

Drug interactions

Ampicillin
Moderate
Textbook

Effective against β-lactamase producing H. influenzae, N. gonorrhoeae and other organisms.

Source: KDT 7e · p698

Related guidelines

Heart failure in diabetes
RSSDI · Cardiology · 2023
Community-acquired pneumonia
ICMR · Pulmonology · 2022
Hypertension in adults
ICMR · Cardiology · 2019
Hypertrophic cardiomyopathy
ESC · Cardiology · 2026
Diabetes management in chronic kidney disease
KDIGO · Nephrology · 2022

Other β-Lactamase Inhibitor drugs

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Sources: KD Tripathi 7e, Goodman & Gilman 14e·Verified: 2026-05-10 · House clinical team