Cilostazole
Contraindicated
Textbook
Increased plasma levels and toxicity of cilostazole.
Should not be administered along with inhibitors of CYP3A4.
Source: KDT 7e · p555
Drug reference
Telithromycin
Macrolide · Antibiotic
Also known as KETEK
MacrolideAntibiotic
CDSCO approvedSchedule H
EXCRETION
—
not curated
INTERACTIONS
12 major
incl. contraindicated
PREGNANCY
C
FDA category + note
Top interactionssee all 12 →
- CilostazoleContraindicatedTextbookKDT 7e · p555
- AbemaciclibSevereDatabaseDDInter
- AcalabrutinibSevereDatabaseDDInter
- AlfentanilSevereDatabaseDDInter
Mechanism
Telithromycin is a ketolide, a semisynthetic derivative of erythromycin. Its structural modifications, including a 3-keto group and a substituted carbamate at C11-C12, reduce its susceptibility to methylase-mediated (erm) and efflux-mediated (mef or msr) resistance mechanisms. This allows it to remain active against many macrolide-resistant gram-positive strains.
Indications
Infections caused by macrolide-resistant gram-positive strains
Dosing
- Adult
- are available in the U.S. Dosing of acarbose and miglitol are similar. Both are provided as 25, 50, or 100 mg tablets that are taken. <30 mL/minute.. >20 mL/minute).. did not exceed 1000 mg/dL, and no associated pancreatitis was documented; nonetheless, colesevelam should be used cautiously in. patients with plasma triglycerides >200 mg/dL. Colesevelam has no
Pharmacokinetics
Bioavailability
57 (41–112)%
Protein binding
70%
Excretion
23 (19–27)%
Side effects
Common
NauseaVomitingDiarrheaAbdominal pain
Serious
- Substantial hepatotoxicity
- QTc interval prolongation
- Exacerbation of myasthenia gravis
- Tinnitus and reversible deafness (especially in elderly)
Pregnancy & lactation
Pregnancy
C
Drug interactions
Abemaciclib
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Acalabrutinib
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Alfentanil
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Alfuzosin
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Amisulpride
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Anagrelide
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Apalutamide
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Apixaban
Severe
Database
Drug interaction classified as: absorption, metabolism
Source: DDInter
Arsenic Trioxide
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Astemizole
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Atorvastatin
Severe
Database
Drug interaction classified as: metabolism.
Source: DDInter
Related guidelines
Other Macrolide drugs
Ask House about Telithromycin
Continue into a citation-backed clinical answer with the drug context already attached.
Sources: Goodman & Gilman 14e, Harrison 22e·Verified: 2026-05-10 · House clinical team