Moclobemide
Severe
Textbook
Increased risk of adverse cardiovascular effects.
At least 2 weeks should elapse between the use of MAO inhibitors and administration of β2 agonists or other sympathomimetics.
Source: G&G 14e · p264
Drug reference
terbutaline
β2-selective bronchodilator · Bronchodilator
β2-selective bronchodilatorBronchodilatorATC R03AC03
CDSCO approvedATC R03AC03
EXCRETION
—
not curated
INTERACTIONS
12 major
SEVERE in our sources
PREGNANCY
B
FDA category + note
Top interactionssee all 12 →
- MoclobemideSevereTextbookG&G 14e · p264
- AmiodaroneSevereDatabaseDDInter
- AmisulprideSevereDatabaseDDInter
- AnagrelideSevereDatabaseDDInter
Mechanism
Terbutaline is a β2-selective bronchodilator, containing a resorcinol ring, making it not a substrate for COMT methylation. It relaxes bronchial smooth muscle.
Indications
long-term treatment of obstructive airway diseasesacute bronchospasmemergency treatment of status asthmaticusAsthmainhibition of preterm labor (tocolysis, off-label)Bronchial asthmaUterine relaxantBronchospasm reversal
Dosing
- Adult
- 5 mg oral, 0.25 mg s.c., 250 µg by inhalation
Pharmacokinetics
Onset
rapid (inhalation or parenteral); delayed 1 to 2 h (oral)
Duration
~3-4 h
Protein binding
action may persist 3 to 6 h (after inhalation)
Side effects
Common
Muscle tremorTachycardiaPalpitationshypotensionpulmonary edema
Serious
- Hypokalemia
- Ventilation-perfusion (V/Q) mismatch (fall in arterial oxygen tension)
- Metabolic effects (increase in free fatty acid, insulin, glucose, pyruvate, and lactate)
Pregnancy & lactation
Pregnancy
B
Drug interactions
Amiodarone
Severe
Database
Drug interaction classified as: synergy.
Source: DDInter
Amisulpride
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Anagrelide
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Arsenic Trioxide
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Bedaquiline
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Bepridil
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Cabozantinib
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Carteolol
Severe
Database
Drug interaction classified as: antagonism
Source: DDInter
Carvedilol
Severe
Database
Drug interaction classified as: antagonism
Source: DDInter
Ceritinib
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Cisapride
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Related guidelines
Ask House about terbutaline
Continue into a citation-backed clinical answer with the drug context already attached.
Sources: KD Tripathi 7e, Goodman & Gilman 14e·Verified: 2026-05-10 · House clinical team