Abemaciclib
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Drug reference
troleandomycin
Antibiotic
Antibiotic
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
12 major
SEVERE in our sources
PREGNANCY
—
not curated
Top interactionssee all 12 →
- AbemaciclibSevereDatabaseDDInter
- AcalabrutinibSevereDatabaseDDInter
- AlfentanilSevereDatabaseDDInter
- AlfuzosinSevereDatabaseDDInter
Mechanism
Troleandomycin activates the pregnane X receptor (PXR).
Drug interactions
Acalabrutinib
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Alfentanil
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Alfuzosin
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Amiodarone
Severe
Database
Drug interaction classified as: synergy, metabolism
Source: DDInter
Artemether
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Atorvastatin
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Avanafil
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Avapritinib
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Axitinib
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Benzhydrocodone
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Bosutinib
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Related guidelines
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Other Antibiotic drugs
Ask House about troleandomycin
Continue into a citation-backed clinical answer with the drug context already attached.
Sources: Goodman & Gilman 14e·Verified: 2026-05-10 · House clinical team