Drug reference

Varicella-Zoster Immunoglobulin

Immunosuppressant · Immunoprophylaxis

ImmunosuppressantImmunoprophylaxis

CDSCO approvedSchedule H

EXCRETION

—

not curated

INTERACTIONS

—

none in our sources

PREGNANCY

—

not curated

Mechanism

Varicella-Zoster Immunoglobulin provides passive immunity to individuals exposed to the varicella-zoster virus. It contains pre-formed antibodies that bind to and neutralize the virus, thereby preventing or mitigating the severity of chickenpox or herpes zoster.

Indications

Prophylaxis in individuals exposed to chickenpox and at special risk of complications

Dosing

Adult: membranes. It is used by mouth for severe herpetic stomatitis. Aciclovir eye ointment is used for herpes simplex infections of the eye; it is combined with systemic treatment for ophthalmic zoster. Famciclovir p. 672, a prodrug of penciclovir, is similar to aciclovir and is licensed for use in herpes zoster and genital herpes. Valaciclovir p.…