Bexarotene
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Drug reference
Clomifene
Aromatase Inhibitor · Infertility agent
Also known as Clomifene citrate, Clomid, Serophene, Milophene
Aromatase InhibitorInfertility agent
CDSCO approvedSchedule H
EXCRETION
—
not curated
INTERACTIONS
1 major
SEVERE in our sources
PREGNANCY
Possible effects on fetal development. Exclude pregnancy before treatment.
FDA category + note
Top interactions
- BexaroteneSevereDatabaseDDInter
Mechanism
Clomifene is an anti-estrogen. It acts as a pure antagonist in all tissues studied.
Indications
Treatment of infertility in anovulatory women
Dosing
- Hepatic adjustment
- Avoid in liver disease or history of liver dysfunction
Contraindications
- Pregnancy
- Liver disease or history of liver dysfunction
- Sex hormone responsive conditions
- Uterine fibroids
Side effects
Common
Abdominal distensionAlopeciaAnxietyBreast tendernessDizzinessFatigueHeadacheHot flushInsomniaMenstrual cycle irregularitiesMood alteredNauseaParaesthesiaSkin reactionsVertigoVision disordersVomiting
Serious
- Angioedema
- Cataract
- Cerebral thrombosis
- Depression
- Disorientation
- Hypertriglyceridaemia
- Jaundice cholestatic
- Neoplasms
- Nervous system disorders
- Optic neuritis
- Ovarian and fallopian tube disorders
- Palpitations
- Pancreatitis
- Psychosis
- Seizure
- Speech disorder
- Stroke
- Syncope
- Tachycardia
- Uterine disorders
- Visual impairment
Pregnancy & lactation
Pregnancy
Possible effects on fetal development. Exclude pregnancy before treatment.
Lactation
May inhibit lactation
Drug interactions
1 additional low-confidence interaction hidden — those rows lack a documented mechanism or management plan in our sources.
Related guidelines
Other Aromatase Inhibitor drugs
Ask House about Clomifene
Continue into a citation-backed clinical answer with the drug context already attached.
Sources: BNF·Verified: 2026-05-10 · House clinical team