Drug reference

Follitropin alfa

GnRH Analogue · Infertility Treatment

Also known as rFSH

GnRH AnalogueInfertility Treatment

CDSCO approvedSchedule H

EXCRETION

—

not curated

INTERACTIONS

—

none in our sources

PREGNANCY

—

not curated

Mechanism

Follitropin alfa, a recombinant form of Follicle-Stimulating Hormone (rFSH), exerts its effects through G protein-coupled receptors in reproductive tissues. In women, it stimulates estrogen secretion and follicle development. This action is crucial for fertility treatment.

Indications

Stimulation of follicular development in infertile hypogonadotropic hypogonadal women with profound LH deficiency (<1.2 IU/L)Ovarian stimulationIn vitro fertilizationMale infertility (hypogonadotropic hypogonadism, to fully induce spermatogenesis when hCG alone is insufficient)ovulation inductioncontrolled ovarian hyperstimulation (for IVF)Replaces urine derived FSH for induction of ovulation and in vitro fertilization

Dosing

Adult: range of doses that are generally regarded as being suitable for adults. Complementary and alternative medicine Prescribing unlicensed medicines An increasing amount of information on complementary and alternative medicine is becoming available.…