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haemophilus influenzae type b vaccine

conjugated bacterial polysaccharide vaccine · vaccine

conjugated bacterial polysaccharide vaccinevaccine
CDSCO approved
EXCRETION
not curated
INTERACTIONS
none in our sources
PREGNANCY
not curated

Mechanism

The Haemophilus influenzae type b (Hib) vaccine is a polysaccharide-protein conjugate designed to confer immunity by inducing antibodies to the capsular polysaccharide polyribosylribitol phosphate (PRP).

Indications

prevention of life-threatening childhood bacterial diseases caused by Haemophilus influenzae, including meningitis, bacteremia with sepsis, epiglottitis, buccal, preseptal, and orbital cellulitisProtection of infants and children against H. influenzae meningitisProtection of infants and children against H. influenzae pneumonia

Dosing

Pediatric
Infants 2–6 months: 3 doses (0.5 ml i.m.) at 8-week gaps. 7–11 months: 2 doses. Older than 1 year: only 1 dose.

Pharmacokinetics

Bioavailability
Good antibody response and protection obtained in >90% recipients

Related guidelines

Other conjugated bacterial polysaccharide vaccine drugs

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Sources: KD Tripathi 7e, Goodman & Gilman 14e, Harrison 22e·Verified: 2026-05-10 · House clinical team