Drug reference

human albumin

Plasma expander, Blood product · Plasma expander

Plasma expander, Blood productPlasma expander

CDSCO approved

EXCRETION

—

not curated

INTERACTIONS

—

none in our sources

PREGNANCY

—

not curated

Mechanism

Human albumin, derived from pooled human plasma, exerts colloidal osmotic (oncotic) pressure, thereby retaining fluid in the vascular compartment when infused intravenously. A 20% solution actively draws and holds additional fluid from interstitial tissues.

Indications

Hypovolemia due to loss of plasma/bloodBurns (acute phase only)Hypovolemic and endotoxin shockSevere trauma and extensive tissue damageAcute hypoproteinaemiaAcute liver failureDialysisDilution of blood before cardiopulmonary bypassPriming of heart-lung and dialysis machines