Drug reference directory
Drug reference

nitrendipine

Dihydropyridine calcium channel blocker · Antianginal

Dihydropyridine calcium channel blockerAntianginal
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
—
none in our sources
PREGNANCY
—
not curated

Mechanism

Releases NO from the endothelium and inhibits cAMP phosphodiesterase, contributing to vasodilator action. The endothelial NO may retard atherosclerosis. Does not depress ventricular contractility and A-V conduction.

Indications

HypertensionAngina pectoris

Dosing

Adult
5–20 mg OD

Pharmacokinetics

Half-life
4–12 hours
Bioavailability
10–30%

Drug interactions

1 additional unreviewed or low-confidence interaction hidden because their provenance or source detail is insufficient.

Related guidelines

Other Dihydropyridine calcium channel blocker drugs

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Textbook-sourced·Sources: KD Tripathi 7e·Updated: 2026-05-10