Bupropion
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Drug reference
Oxamniquine
Anthelmintic · Antiparasitic
AnthelminticAntiparasitic
CDSCO approvedSchedule H
EXCRETION
—
not curated
INTERACTIONS
5 major
SEVERE in our sources
PREGNANCY
C
FDA category + note
Top interactionssee all 5 →
- BupropionSevereDatabaseDDInter
- IohexolSevereDatabaseDDInter
- IopamidolSevereDatabaseDDInter
- ThioridazineSevereDatabaseDDInter
Mechanism
Oxamniquine is effective for the treatment of Schistosoma mansoni infections. The precise molecular mechanism of action is not detailed in the provided texts.
Indications
Schistosoma mansoni infectionsIntestinal or hepatic schistosomiasis caused by Schistosoma mansoni
Dosing
- Adult
- after a 400mg oral dose, and its plasma halflife is 8–12 hours. The sulfoxide is mostly proteinbound, distributes well to tissues, and enters bile, cerebrospinal fluid, and hydatid cysts. Albendazole metabolites are excreted in the urine. Benzimidazoles are thought to act against nematodes by inhibiting microtubule synthesis.…
Pharmacokinetics
Bioavailability
well absorbed; food retards absorption and reduces bioavailability
Excretion
about 70% of an administered dose is excreted in urine as a mixture of pharmacologically inactive metabolites
Side effects
Common
dizzinessdrowsinessheadacheorange urineelevated aminotransferases
Serious
- seizures
- hallucinations
Pregnancy & lactation
Pregnancy
C
Drug interactions
Iohexol
Severe
Database
Clinical effect not specified
Source: DDInter
Iopamidol
Severe
Database
Clinical effect not specified
Source: DDInter
Thioridazine
Severe
Database
Clinical effect not specified
Source: DDInter
Tramadol
Severe
Database
Clinical effect not specified
Source: DDInter
7 additional unreviewed or low-confidence interactions hidden because their provenance or source detail is insufficient.
Related guidelines
Other Anthelmintic drugs
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Textbook-sourced·Sources: Harrison 22e, Katzung·Updated: 2026-05-13