Acalabrutinib
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Drug reference
Fosamprenavir
Antiretroviral
Also known as FOS-APV
Antiretroviral
CDSCO approvedSchedule H
EXCRETION
—
not curated
INTERACTIONS
12 major
SEVERE in our sources
PREGNANCY
Manufacturer advises use only if potential
FDA category + note
Top interactionssee all 12 →
- AcalabrutinibSevereDatabaseDDInter
- AlfentanilSevereDatabaseDDInter
- AlfuzosinSevereDatabaseDDInter
- AmiodaroneSevereDatabaseDDInter
Mechanism
Fosamprenavir is a protease inhibitor that functions by inhibiting the HIV protease enzyme, crucial for viral maturation. It is also a strong inhibitor of the cytochrome P450 3A4 (CYP3A4) enzyme.
Indications
HIV/AIDS treatment
Dosing
- Adult
- low-dose ritonavir (r). They boost the concentrations of other antiretrovirals metabolised by CYP3A4, but have no antiretroviral activity themselves. ANTIVIRALS › HIV-FUSION INHIBITORS Enfuvirtide l DRUG ACTION 14-Jul-2018 Enfuvirtide inhibits the fusion of HIV to the host cell.…
Pharmacokinetics
Metabolism
Metabolized by CYP3A4
Pregnancy & lactation
Pregnancy
Manufacturer advises use only if potential
Drug interactions
Alfentanil
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Alfuzosin
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Amiodarone
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Artemether
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Astemizole
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Atorvastatin
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Avanafil
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Avapritinib
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Axitinib
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Benzhydrocodone
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Bepridil
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Related guidelines
Other Antiretroviral drugs
Ask House about Fosamprenavir
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Sources: BNF·Verified: 2026-05-13 · House clinical team