Sulconazole

Sulconazole is an imidazole antifungal that inhibits lanosterol 14-α-demethylase (CYP51) in the ergosterol biosynthetic pathway. Applied topically as sulconazole nitrate, it is effective against dermatophytes (Trichophyton, Microsporum, Epidermophyton) and Candida species. Like other imidazoles, it has limited selectivity for fungal over mammalian P450 enzymes, restricting use to topical formulations.

Adult

headache are common reactions that may be decreased by intrathecal administration of 10-15 mg of hydrocortisone. Local injections. 0.7 mg/kg, at the start of the infusion decreases reactions. Febrile. treatment unless the cumulative dose exceeds 3-4 g. Renal tubular