Abciximab
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Drug reference
Tipranavir
Antiretroviral
Also known as TPV, APTIVUS
Antiretroviral
CDSCO approvedSchedule H
EXCRETION
—
not curated
INTERACTIONS
12 major
SEVERE in our sources
PREGNANCY
Manufacturer advises use only if potential
FDA category + note
Top interactionssee all 12 →
- AbciximabSevereDatabaseDDInter
- AcalabrutinibSevereDatabaseDDInter
- AlteplaseSevereDatabaseDDInter
- Aminolevulinic AcidSevereDatabaseDDInter
Mechanism
Protease inhibitors block the activity of HIV protease, an enzyme crucial for the processing of viral polyproteins into mature functional proteins. This inhibition prevents the assembly of new, infectious viral particles, thereby hindering HIV replication.
Indications
Treatment of HIV/AIDSManagement of HIV infection in treatment-experienced patients with resistance to other approved drugs
Dosing
- Adult
- low-dose ritonavir (r). They boost the concentrations of other antiretrovirals metabolised by CYP3A4, but have no antiretroviral activity themselves. ANTIVIRALS › HIV-FUSION INHIBITORS Enfuvirtide l DRUG ACTION 14-Jul-2018 Enfuvirtide inhibits the fusion of HIV to the host cell.…
Pharmacokinetics
Metabolism
Metabolized by CYP3A4
Pregnancy & lactation
Pregnancy
Manufacturer advises use only if potential
Drug interactions
Acalabrutinib
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Alteplase
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Aminolevulinic Acid
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Amprenavir
Severe
Database
Drug interaction classified as: others
Source: DDInter
Anagrelide
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Anisindione
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Anistreplase
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Antithrombin Iii Human
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Apixaban
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Ardeparin
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Argatroban
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Related guidelines
Antimicrobial resistance — clinical roadmap
MOHFW · Infectious Diseases · 2012
Antiretroviral therapy for HIV
NACO · Infectious Diseases · 2018
Skin and soft tissue infections
IDSA · Infectious Diseases · 2010
Hepatitis B — chronic infection
EASL · Gastroenterology · 2025
Urinary tract infection
EAU · Urology · 2024
Other Antiretroviral drugs
Ask House about Tipranavir
Continue into a citation-backed clinical answer with the drug context already attached.
Sources: BNF·Verified: 2026-05-13 · House clinical team