Drug reference
Alclometasone
Corticosteroid · Anti-inflammatory
Also known as Alclometasone dipropionate, ACLOVATE
CorticosteroidAnti-inflammatory
CDSCO approvedSchedule H
EXCRETION
—
not curated
INTERACTIONS
—
none in our sources
PREGNANCY
—
not curated
Mechanism
Alclometasone dipropionate is a moderate-potency topical corticosteroid that acts by binding to glucocorticoid receptors. This binding modulates the transcription of various genes, leading to reduced synthesis of inflammatory mediators. The overall effect is a decrease in inflammation, vasoconstriction, and immunosuppression, which alleviates symptoms of inflammatory skin disorders.
Indications
Inflammatory skin disorders such as eczemas
Dosing
- Adult
- Apply thinly 1–2 times a day to affected areas.
- Pediatric
- Apply thinly 1–2 times a day to affected areas (licensed for use in children, age range not specified). Wet-wrap bandaging increases absorption and should be initiated by a dermatologist with supervised application.
Side effects
Serious
- Growth arrest (in children)
- Fat redistribution
- Striae
- Ecchymoses
- Hypokalemic alkalosis
- Hypertension
- Hyperglycemia with glycosuria
- Increased susceptibility to infection
- Reactivation of latent tuberculosis
Related guidelines
Hypertensive disorders of pregnancy
FOGSI · Obstetrics & Gynaecology · 2019
Inflammatory bowel disease
OTHER · Gastroenterology · 2015
Substance use disorders
NIMHANS · Psychiatry · 2022
Preventive care in inflammatory bowel disease
ACG · Gastroenterology · 2025
Primary headache disorders
NICE · Neurology · 2021
Other Corticosteroid drugs
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Sources: Katzung, BNF, Harriet Lane·Verified: 2026-05-10 · House clinical team