Betamethasone dipropionate

As a topical corticosteroid (glucocorticoid), Betamethasone dipropionate reduces inflammation and immune responses in the skin by binding to intracellular glucocorticoid receptors, which then modulate gene expression to inhibit the synthesis of pro-inflammatory mediators.

Adult

Apply topically twice daily. More frequent application does not improve response.

Pediatric

For severe atopic eczema on the limbs, a potent corticosteroid may be appropriate for 1-2 weeks only, switching to a less potent preparation as the condition improves. For acute flare-ups, more potent formulations may be used for a short period. Very potent corticosteroids should be initiated under the supervision of a specialist.

• Avoid use on the face or in occluded areas such as the axillae or groin if fluorinated.