Alclometasone dipropionate

Corticosteroids exert anti-inflammatory and immunosuppressive effects. They act by binding to glucocorticoid receptors in target cells, which then translocate to the nucleus and modulate gene expression, leading to the synthesis of anti-inflammatory proteins and inhibition of pro-inflammatory mediators.

Adult

Apply 1–2 times a day, to be applied thinly. Topical corticosteroid preparations should be applied no more frequently than twice daily; once daily is often sufficient. Spread thinly on the skin but in sufficient quantity to cover the affected areas.

Pediatric

Apply 1–2 times a day, to be applied thinly. Licensed for use in children (age range not specified by manufacturer). 'Wet-wrap bandaging' increases absorption into the skin, but should be initiated only by a dermatologist and application supervised by a healthcare professional trained in the technique.