Drug reference directory
Drug reference

Lactic acid

Retinoid · Dermatological

RetinoidDermatological
CDSCO approvedSchedule H
EXCRETION
—
not curated
INTERACTIONS
—
none in our sources
PREGNANCY
—
not curated

Mechanism

Lactic acid is an alpha-hydroxy acid (AHA) used topically as a keratolytic and humectant. It reduces the pH of the stratum corneum, disrupting intercorneocyte cohesion by dissolving the intercellular cement, promoting desquamation and skin renewal. At lower concentrations it acts as a moisturizer by enhancing water retention in the stratum corneum through its hygroscopic properties.

Dosing

Adult
▶ When used by inhalation Oral irritation . throat irritation ▶ With parenteral use Pulmonary oedema ▶ Frequency not known ▶ With parenteral use Lactic acidosis (with high doses) . vomiting l BREAST FEEDING Inhaled drugs for asthma can be taken as normal during breast-feeding.…

Drug interactions

12 additional unreviewed or low-confidence interactions hidden because their provenance or source detail is insufficient.

Related guidelines

Other Retinoid drugs

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Textbook-sourced·Sources: BNF·Updated: 2026-05-13