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Diflorasone

Corticosteroid · Anti-inflammatory

Also known as Diflorasone diacetate, PSORCON, Florone, Maxiflor

CorticosteroidAnti-inflammatory
CDSCO approvedSchedule H
EXCRETION
not curated
INTERACTIONS
none in our sources
PREGNANCY
not curated

Mechanism

Diflorasone, a synthetic glucocorticoid, exerts multiple effects to inhibit the immune system and the inflammatory response. This action helps to reduce inflammation and suppress immune reactions in the treated area.

Indications

Psoriasis

Dosing

Adult
Corticosteroids are only minimally absorbed following application to normal skin; for example, approximately 1% of a dose of hydrocortisone solution applied to the ventral forearm is absorbed. Long­term occlusion with an impermeable film such as plastic wrap is an effective method of enhancing penetration, yielding a 10­fold increase in absorption.…

Contraindications

  • Known infections of some consequence (use only if absolutely necessary and concomitantly with appropriate antimicrobial or antifungal therapy)
  • Latent tuberculosis (risk for reactivation)

Side effects

Common
Increased susceptibility to infectionHyperglycemia (in diabetic patients)
Serious
  • Reactivation of latent tuberculosis

Related guidelines

Other Corticosteroid drugs

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Sources: Katzung·Verified: 2026-05-13 · House clinical team